Although supplement marketers claim that it can reduce appetite, there's very little published research in humans. Glucomannan, a soluble fiber-rich substance extracted from the root of the konjac plant, has gained popularity as a weight-loss aid. Proponents of glucomannan claim that it suppresses appetite because the soluble fiber attracts water and turns to gel during digestion. Although proponents of the supplement claim that CLA may decrease fat while building muscle, research results have yielded mixed results and insufficient evidence.

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